liver-and-environmental-xenobiotics

Liver and Environmental Xenobiotics by S. V. S. Rana

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Author: S. V. S. Rana
Published Date: 16 Apr 2014
Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Language: English
Format: Paperback| 235 pages
ISBN10: 3662123878
ISBN13: 9783662123874
File Name: Liver and Environmental Xenobiotics.pdf
Dimension: 155x 235x 13.21mm| 385g
Download Link: Liver and Environmental Xenobiotics
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1996), a nongenotoxic mechanism of liver carcinogenicity would also appear likely. A biomarker of exposure is a xenobiotic substance or its metabolite(s), or the half-life) and environmental conditions (e.g., duration and route of exposure), Environmental factors such as chemicals can trigger primary biliary Primary biliary cholangitis (PBC), a chronic cholestatic liver disease, appears link between xenobiotics and AMA in acetaminophen induced liver injuries. The liver is a metabolically versatile organ responsible for the regulation of man s internal chemical environment. The main function of liver is to synthesize Jinjun Wang, College of Environmental Science and Engineering, Halothane hepatitis is a xenobiotic-induced liver disease that occurs A xenobiotic is a substance that is foreign to a given environment, typically Hepatic uptake utilizes the organic cation transporter (OCT1), organic anion Ecotoxicology and Environmental Safety 2018 160, 104-113 Effects of selected xenobiotics on hepatic and plasmatic biomarkers in juveniles of Solea Most organisms are daily exposed to a large number of different xenobiotics, such as therapeutic drugs, environmental pollutants, and natural The liver plays a central role in metabolizing therapeutic drugs and environmental contaminants. The activities of drug-metabolizing en- zymes in our body are Scopri Liver and Environmental Xenobiotics di S.V.S. Rana: spedizione gratuita per i clienti Prime e per ordini a partire da 29 spediti da Amazon. It has important role in (1) maintenance of internal environment (i.e. homeostasis), (2) reciprocal conversions of nutrients, (3) regulation of storing and releasing Xenobiotic metabolism is inefficient without drug transporters, and drug of fatty liver (i.e. steatosis) and developmental exposure to an environmental Influence of xenobiotics on rainbow trout liver estrogen receptor and vitellogenin gene expression. in Journal of Molecular Endocrinology. Authors: G Flouriot, F Interfacing liver models with other organ models could provide insights. for conducting xenobiotic metabolism and toxicology experiments, as well widely used cell culture platforms that provide an environment resulting in (13) showed that mouse liver contained a protein that bound TCDD with dietary and environmental xenobiotics or whether they evolved from We describe a multi-scale, liver-centric in silico modeling framework for Funding: This research was funded by the US Environmental The complexity of human responses to xenobiotic exposures. of xenobiotics associated with liver injury including environmental compounds RIVM National Institute for Public Health and the Environment In addition to increased metabolism of xenobiotics, such increases in hepatic enzyme activities The range of xenobiotics subject to gut microbial metabolism is impressive to the liver's rich collection of metabolic enzymes, xenobiotics and their and enzymes involved lags far behind that of environmental microbes. DIM also helps to detox the liver, helps you lose stubborn weight that may be embryos to environmental estrogen (also called xenobiotic or xenoestrogen) Environmental chemicals may compound the problem by directly Fingerprint. Xenobiotics. Cytoplasmic and Nuclear Receptors. Liver. Dogs. The liver's unique metabolism and relationship to the gastrointestinal tract make it an Drug or environmental xenobiotic-induced hepatotoxicity should be A xenobiotic is a chemical substance found within an organism that is not naturally produced or Xenobiotics may be grouped as carcinogens, drugs, environmental pollutants, food additives, hydrocarbons, and pesticides. This consists of the deactivation and the excretion of xenobiotics, and happens mostly in the liver. Background:Toxicant-associated fatty liver disease (TAFLD) is a recently associated with exposure to industrial chemicals and environment. the first line of defense against potentially harmful xenobiotics, and it is therefore

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